Research Article

Experimental Study of Antiatherosclerosis Effects with Hederagenin in Rats

Table 1

Comparison of rat hemorheological parameters in each group. versus normal group; versus model group; versus atorvastatin calcium group.

GroupWhole-blood viscosity/mpa·sHematocrit Erythrocyte aggregation index Platelet aggregation rate/%
Low shearMid shearHigh shearViscosity

Normal10.76 ± 0.837.15 ± 0.725.18 ± 0.421.28 ± 0.120.41 ± 0.045.12 ± 0.3339.22 ± 3.69
Model19.23 ± 2.51a9.66 ± 0.89a7.33 ± 0.76a1.81 ± 0.23a0.69 ± 0.12a6.51 ± 0.87a59.03 ± 5.17a
Lipitor12.64 ± 0.97b7.32 ± 0.83b6.26 ± 0.58b1.32 ± 0.15b0.52 ± 0.05b5.28 ± 0.39b46.61 ± 4.09b
Hederagenin12.58 ± 0.89b7.27 ± 0.71b5.66 ± 0.53bc1.37 ± 0.14b0.53 ± 0.03b5.37 ± 0.45b46.38 ± 4.19b