Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6

Figure 2

Cytotoxicity of paeoniflorin and albiflorin on HepG2 cells. Cells cultured in the 96-well plate for 24 h were incubated with paeoniflorin and albiflorin (10⁻³–10⁻¹⁰ M), respectively, for 18 h. After MTT reagent (10 μL per well) was added for additional 2 h, the absorbance was recorded at 570 nm and cells viability was represented as the percent decrease compared to the control cells. Values are means ± SD () from three independent experiments and there is no significant difference compared with control group cells.