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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 473056, 7 pages
Research Article

Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism

1Department of Family Medicine, Ewha Woman’s University Mokdong Hospital, Ewha Woman’s University School of Medicine, Seoul, Republic of Korea
2Health Promotion Center, Ewha Woman’s University Mokdong Hospital, Seoul 158-710, Republic of Korea

Received 13 January 2015; Accepted 6 May 2015

Academic Editor: José L. Ríos

Copyright © 2015 A Ri Byun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. Barley sprout (Hordeum vulgare L.) contains 4.97% fat, 52.6% polysaccharide, and 34.1% protein along with a variety of vitamins, minerals, and polyphenolic compounds. Hexacosanol is one such compound from the barley leaf that might improve cholesterol metabolism by decreasing cholesterol synthesis. Method. Therefore, this study was conducted to investigate the effects of barley sprout extract on serum lipid metabolism in healthy volunteers . Subjects were randomly divided into two groups: one group consumed a single capsule of barley leaf extract daily (, 42.48 ± 13.58 years) and the other consumed placebo capsules (, 40.54 ± 11.1 years) for 12 weeks. Results. After 12 weeks, total cholesterol and low-density lipoprotein- (LDL-) cholesterol were not lower in the barley sprout extract group compared to the placebo group ( and , resp.) and no differences in clinical or laboratory findings were observed between both groups. Conclusion. Our study failed to show significant lipid-lowering effects of barley sprout extract, possibly due to dosage, duration of therapy, and small sample size. Despite our nonsignificant findings, barley sprout has a possibility as a functional health food; therefore future research is needed.