The Combination of Resveratrol and Quercetin Attenuates Metabolic Syndrome in Rats by Modifying the Serum Fatty Acid Composition and by Upregulating SIRT 1 and SIRT 2 Expression in White Adipose Tissue

Table 1

The effects of RSV + QRC administration on body characteristics and biochemical parameters from control and MetS rats.

	Control			MetS
	Without treatment	RSV 10 + QRC 0.19 mg/kg/day	RSV 50 + QRC 0.95 mg/kg/day	Without treatment	RSV 10 + QRC 0.19 mg/kg/day	RSV 50 + QRC 0.95 mg/kg/day
Body weight (g)	502.0 ± 19.5	463.8 ± 20.8	514.2 ± 20.9	570.4 ± 13.4^a	490.8 ± 11.6^c	489.8 ± 10.5^c
Central adiposity (g)	6.0 ± 0.7	4.5 ± 0.6	6.3 ± 0.9	12 ± 0.6^a	11.5 ± 0.9	8.9 ± 1.1^c
Blood pressure (mm Hg)	103.3 ± 1.0	101.2 ± 2.7	108.4 ± 3.5	140.5 ± 1.0^a	122.7 ± 3.8^c	115.5 ± 2.9^c
Glucose (mg/dL)	119.9 ± 12.2	118.8 ± 13.7	87.9 ± 5.9	121.8 ± 20.3	85.3 ± 9.5	90.7 ± 7.7
Insulin (ng/mL)	0.26 ± 0.02	0.25 ± 0.05	0.18 ± 0.04	0.47 ± 0.04^a	0.29 ± 0.05^c	0.23 ± 0.02^c
HOMA-IR	1.3 ± 0.2	0.61 ± 0.03	0.9 ± 0.12	2.1 ± 0.3^b	0.9 ± 0.1^c	0.81 ± 0.1^c
Leptin (ng/mL)	2.3 ± 0.3	3.3 ± 0.3	2.6 ± 0.1	4.2 ± 0.3^a	5.2 ± 0.3^d,e	3.8 ± 0.3^e
Adiponectin (g/mL)	3.8 ± 0.2	4.2 ± 0.3	3.7 ± 0.3	6.7 ± 0.3^a	6.1 ± 0.5^e	5.8 ± 0.2^e

Values are mean ± SEM. HOMA-IR: homeostatic model assessment of insulin resistance; ; MetS without treatment versus control without treatment; MetS without treatment versus control without treatment; against same group without treatment; versus same group with different doses; against control with same dose.