The Combination of Resveratrol and Quercetin Attenuates Metabolic Syndrome in Rats by Modifying the Serum Fatty Acid Composition and by Upregulating SIRT 1 and SIRT 2 Expression in White Adipose Tissue
Table 3
Effect of RSV + QRC administration on seric fatty acid (FA) composition from control and MetS rats.
FA %
Control
MetS
Without treatment
RSV 10 + QRC 0.19 mg/kg/day
RSV 50 + QRC 0.95 mg/kg/day
Without treatment
RSV 10 + QRC 0.19 mg/kg/day
RSV 50 + QRC 0.95 mg/kg/day
Palmitic acid
32.7 ± 0.9
31.7 ± 0.6
32.1 ± 1.2
33.5 ± 0.6
32.7 ± 1.1
32.2 ± 1.2
Palmitoleic acid
4.3 ± 0.7
5.6 ± 1.1
4.5 ± 0.8
6.7 ± 0.3
6.2 ± 0.5
7.3 ± 0.6
Stearic acid
22.2 ± 0.9
22.8 ± 0.9
22.6 ± 1.1
19.4 ± 1.1
19.5 ± 1.0
19.8 ± 0.5
Oleic acid
14.3 ± 1.1
13.5 ± 0.6
13.3 ± 0.7
21.9 ± 1.3
22.1 ± 0.4
17.7 ± 1.1
Linoleic acid
13.6 ± 0.8
12.6 ± 0.8
14.1 ± 0.9
10.5 ± 1.2
11.3 ± 0.7
10.3 ± 0.5
-linoleic acid
0.3 ± 0.03
0.9 ± 0.4
0.4 ± 0.1
0.8 ± 0.3
0.5 ± 0.1
0.3 ± 0.1
Dihomo--linoleic acid
1.2 ± 0.5
0.6 ± 0.1
0.6 ± 0.2
0.7 ± 0.4
0.4 ± 0.05
0.8 ± 0.4
Arachidonic acid
5.5 ± 1.1
10.7 ± 1.1
12.1 ± 0.9
6.7 ± 0.9
7.9 ± 0.6
7.3 ± 0.4
SFA
59.9 ± 1.4
55.9 ± 2.0
54.7 ± 1.7
54.0 ± 1.5
52.3 ± 1.5
52.7 ± 1.7
MUFA
17.8 ± 1.0
19.0 ± 1.4
17.8 ± 0.8
28.6 ± 1.6
27.6 ± 0.5
25.6 ± 1.4
PUFA
20.3 ± 1.6
23.5 ± 1.2
27.2 ± 1.6
15.3 ± 0.8
20.1 ± 1.2
19.2 ± 0.5
SFA: saturated fatty acid, MUFA: monounsaturated fatty acid, and PUFA: polyunsaturated fatty acid. Data are mean ± SEM. ; MetS without treatment versus control without treatment; against same group without treatment; versus same group with different dose.
