Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 506413, 9 pages
http://dx.doi.org/10.1155/2015/506413
Research Article

In Vitro Pharmacological Activities and GC-MS Analysis of Different Solvent Extracts of Lantana camara Leaves Collected from Tropical Region of Malaysia

1Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia (UPM), 43400 Serdang, Selangor, Malaysia
2Institute of Tropical Agriculture, Universiti Putra Malaysia (UPM), 43400 Serdang, Selangor, Malaysia

Received 18 September 2015; Revised 19 November 2015; Accepted 22 November 2015

Academic Editor: Rahmatullah Qureshi

Copyright © 2015 Mallappa Kumara Swamy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Z. Gezahegn, M. S. Akhtar, D. Woyessa, and Y. Tariku, “Antibacterial potential of Thevetia peruviana leaf extracts against food associated bacterial pathogens,” Journal of Coastal Life Medicine, vol. 3, no. 2, pp. 150–157, 2015. View at Publisher · View at Google Scholar
  2. M. K. Swamy and U. R. Sinniah, “A Comprehensive review on the phytochemical constituents and pharmacological activities of Pogostemon cablin Benth.: an Aromatic Medicinal Plant of Industrial Importance,” Molecules, vol. 20, no. 5, pp. 8521–8547, 2015. View at Publisher · View at Google Scholar
  3. D. A. Lobo, R. Velayudhan, P. Chatterjee, H. Kohli, and P. J. Hotez, “The neglected tropical diseases of India and South Asia: review of their prevalence, distribution, and control or elimination,” PLoS Neglected Tropical Diseases, vol. 5, no. 10, Article ID e1222, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. R. C. Moellering Jr., J. R. Graybill, J. E. McGowan Jr., and L. Corey, “Antimicrobial resistance prevention initiative-an update: proceedings of an expert panel on resistance,” American Journal of Infection Control, vol. 35, no. 9, p. -S23, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. I. M. Ayoub, M. El-Shazly, M.-C. Lu, and A. N. B. Singab, “Antimicrobial and cytotoxic activities of the crude extracts of Dietes bicolor leaves, flowers and rhizomes,” South African Journal of Botany, vol. 95, pp. 97–101, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. S. K. Mohanty, K. Malappa, A. Godavarthi, B. Subbanarasiman, and A. Maniyam, “Evaluation of antioxidant, in vitro cytotoxicity of micropropagated and naturally grown plants of Leptadenia reticulata (Retz.) Wight & Arn.-an endangered medicinal plant,” Asian Pacific Journal of Tropical Medicine, vol. 7, no. 1, pp. S267–S271, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. E. L. Ghisalberti, “Lantana camara L. (Verbenaceae),” Fitoterapia, vol. 71, no. 5, pp. 467–486, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Kumar, R. Sandhir, and S. Ojha, “Evaluation of antioxidant activity and total phenol in different varieties of Lantana camara leaves,” BMC Research Notes, vol. 7, no. 1, p. 560, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Patel, “A weed with multiple utility: lantana camara,” Reviews in Environmental Science and Biotechnology, vol. 10, no. 4, pp. 341–351, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Venkatachalam, V. K. Kumar, P. K. Selvi, A. O. Maske, and N. S. Kumar, “Physicochemical and preliminary phytochemical studies on the Lantana camara (L.) fruits,” International Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, no. 1, pp. 52–54, 2011. View at Google Scholar · View at Scopus
  11. J. A. Parrotta, Healing Plants of Peninsular India, CABI International, New York, NY, USA, 2001.
  12. S. B. Yadav and V. Tripathi, “A new triterpenoid from Lantana camara,” Fitoterapia, vol. 74, no. 3, pp. 320–321, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Saraf, S. Quereshi, K. Sharma, and N. A. Khan, “Antimicrobial activity of Lantana camara L,” Journal of Experimental Sciences, vol. 2, no. 10, pp. 50–54, 2011. View at Google Scholar
  14. D. Ganjewala, S. Sam, and K. Hayat Khan, “Biochemical compositions and antibacterial activities of Lantana camara plants with yellow, lavender, red and white flowers,” EurAsian Journal of Biosciences, vol. 3, no. 10, pp. 69–77, 2009. View at Publisher · View at Google Scholar
  15. B. Mahdi-Pour, S. L. Jothy, L. Y. Latha, Y. Chen, and S. Sasidharan, “Antioxidant activity of methanol extracts of different parts of Lantana camara,” Asian Pacific Journal of Tropical Biomedicine, vol. 2, no. 12, pp. 960–965, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. F. Anwar, N. Shaheen, G. Shabir, M. Ashraf, K. M. Alkharfy, and A.-H. Gilani, “Variation in antioxidant activity and phenolic and flavonoid contents in the flowers and leaves of Ghaneri (Lantana camara L.) as affected by different extraction solven,” International Journal of Pharmacology, vol. 9, no. 7, pp. 442–453, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. O. P. Sharma, J. Vaid, and P. D. Sharma, “Comparison of lantadenes content and toxicity of different taxa of the lantana plant,” Journal of Chemical Ecology, vol. 17, no. 11, pp. 2283–2291, 1991. View at Publisher · View at Google Scholar · View at Scopus
  18. J. B. Harborne, Phytochemical Methods, Chapman & Hall, London, UK, 1998.
  19. N. Pokharen, S. Dahal, and M. Anuradha, “Phytochemical and antimicrobial studies of leaf extract of Euphorbia neriifolia,” Journal of Medicinal Plants Research, vol. 5, no. 24, pp. 5785–5788, 2011. View at Google Scholar
  20. M. Kumara Swamy, K. M. Sudipta, P. Lokesh et al., “Phytochemical screening and in vitro antimicrobial activity of Bougainvillea spectabilis flower extracts,” International Journal of Phytomedicine, vol. 4, no. 3, pp. 375–379, 2012. View at Google Scholar · View at Scopus
  21. R. K. Salar and L. Seasotiya, “Free radical scavenging activity, phenolic contents and phytochemical evaluation of different extracts of stem bark of Butea monosperma (Lam.) kuntze,” Frontiers in Life Science, vol. 5, no. 3-4, pp. 107–116, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Zhishen, T. Mengcheng, and W. Jianming, “The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals,” Food Chemistry, vol. 64, no. 4, pp. 555–559, 1999. View at Publisher · View at Google Scholar · View at Scopus
  23. S. K. Mohanty, K. Malappa, A. Godavarthi, B. Subbanarasiman, and A. Maniyam, “Evaluation of antioxidant, in vitro cytotoxicity of micropropagated and naturally grown plants of Leptadenia reticulata (Retz.) Wight & Arn.-an endangered medicinal plant,” Asian Pacific Journal of Tropical Medicine, vol. 7, supplement 1, pp. S267–S271, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Sultana, F. Anwar, and M. Ashraf, “Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts,” Molecules, vol. 14, no. 6, pp. 2167–2180, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Bhakta and D. Ganjewala, “Effect of leaf positions on total phenolics, flavonoids and proanthocyanidins content and antioxidant activities in Lantana camara (L),” Journal of Scientific Research, vol. 1, no. 2, pp. 363–369, 2009. View at Publisher · View at Google Scholar
  26. R. Naz and A. Bano, “Phytochemical screening, antioxidants and antimicrobial potential of Lantana camara in different solvents,” Asian Pacific Journal of Tropical Disease, vol. 3, no. 6, pp. 480–486, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. C. L. Apetrei, C. Tuchilus, A. C. Aprotosoaie, A. Oprea, K. E. Malterud, and A. Miron, “Chemical, antioxidant and antimicrobial investigations of Pinus cembra L. bark and needles,” Molecules, vol. 16, no. 9, pp. 7773–7788, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. A. Ghasemzadeh and N. Ghasemzadeh, “Flavonoids and phenolic acids: role and biochemical activity in plants and human,” Journal of Medicinal Plant Research, vol. 5, no. 31, pp. 6697–6703, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. V. Lattanzio, V. M. Lattanzio, and A. Cardinali, “Role of phenolics in the resistance mechanisms of plants against fungal pathogens and insects,” Phytochemistry: Advances in Research, vol. 661, pp. 23–67, 2006. View at Google Scholar
  30. J. Dai and R. J. Mumper, “Plant phenolics: extraction, analysis and their antioxidant and anticancer properties,” Molecules, vol. 15, no. 10, pp. 7313–7352, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. R. Manian, N. Anusuya, P. Siddhuraju, and S. Manian, “The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficus bengalensis L. and Ficus racemosa L.,” Food Chemistry, vol. 107, no. 3, pp. 1000–1007, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. P. Kuppusamy, M. M. Yusoff, N. R. Parine, and N. Govindan, “Evaluation of in-vitro antioxidant and antibacterial properties of Commelina nudiflora L. extracts prepared by different polar solvents,” Saudi Journal of Biological Sciences, vol. 22, no. 3, pp. 293–301, 2015. View at Publisher · View at Google Scholar
  33. E. M. Tekwu, A. C. Pieme, and V. P. Beng, “Investigations of antimicrobial activity of some Cameroonian medicinal plant extracts against bacteria and yeast with gastrointestinal relevance,” Journal of Ethnopharmacology, vol. 142, no. 1, pp. 265–273, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. K. Canli, E. M. Altuner, and I. Akata, “Antimicrobial screening of Mnium stellare,” Bangladesh Journal of Pharmacology, vol. 10, no. 2, pp. 321–325, 2015. View at Publisher · View at Google Scholar
  35. M. V. Villegas and J. P. Quinn, “An update on antibiotic-resistant gram-negative bacteria,” Infections in Medicine, vol. 21, no. 12, pp. 595–599, 2004. View at Google Scholar · View at Scopus
  36. R. Preethi, V. V. Devanathan, and M. Loganathan, “Antimicrobial and antioxidant efficacy of some medicinal plants against food borne pathogens,” Advances in Biological Research, vol. 4, no. 2, pp. 122–125, 2010. View at Google Scholar
  37. L. S. Wei, W. Wee, J. Y. F. Siong, and D. F. Syamsumir, “Characterization of anticancer, antimicrobial, antioxidant properties and chemical compositions of Peperomia pellucida leaf extract,” Acta Medica Iranica, vol. 49, no. 10, pp. 670–674, 2011. View at Google Scholar · View at Scopus
  38. J. O. Ban, I. G. Hwang, T. M. Kim et al., “Anti-proliferate and pro-apoptotic effects of 2,3-Dihydro-3,5- dihydroxy-6-methyl-4Hpyranone through inactivation of NF-κB in human colon cancer cells,” Archives of Pharmacal Research, vol. 30, pp. 1455–1463, 2007. View at Google Scholar
  39. N. Sharma, K. W. Samarakoon, R. Gyawali et al., “Evaluation of the antioxidant, anti-inflammatory, and anticancer activities of Euphorbia hirta ethanolic extract,” Molecules, vol. 19, no. 9, pp. 14567–14581, 2014. View at Publisher · View at Google Scholar · View at Scopus
  40. A. I. Hussain, F. Anwar, S. T. H. Sherazi, and R. Przybylski, “Chemical composition, antioxidant and antimicrobial activities of basil (Ocimum basilicum) essential oils depends on seasonal variations,” Food Chemistry, vol. 108, no. 3, pp. 986–995, 2008. View at Publisher · View at Google Scholar · View at Scopus
  41. Y. Rajashekar, A. Raghavendra, and N. Bakthavatsalam, “Acetylcholinesterase inhibition by biofumigant (Coumaran) from leaves of Lantana camara in stored grain and household insect pests,” BioMed Research International, vol. 2014, Article ID 187019, 6 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  42. A. Othman, N. Abdullah, S. Ahmad, I. Ismail, and M. Zakaria, “Elucidation of in-vitro anti-inflammatory bioactive compounds isolated from Jatropha curcas L. plant root,” BMC Complementary and Alternative Medicine, vol. 15, no. 1, p. 11, 2015. View at Publisher · View at Google Scholar