AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation

<div>T cell receptor (TCR) signal transduction is initiated by the recognition of cognate peptide-MHC molecules. The first molecule to be recruited to the TCR-CD3 complex is the SRC family kinase (SFK) member LCK, which phosphorylates immunoreceptor tyrosine-based activation motifs (ITAMs) of the CD3<i>γ</i> chain, CD3<i>δ</i> chain, CD3<i>ε</i> chains, and the <i>ζ</i>-chains.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 6: AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation 

Figure 6 | AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation 