Genistein Attenuates Nonalcoholic Steatohepatitis and Increases Hepatic PPARγ in a Rat Model

Figure 4

Effect of genistein on liver histopathology of NASH in rats. (a) Control group showed a normal structure of the liver; (b) NASH group presented steatohepatitis consisting of numerous fat vacuoles, inflammatory cells, and balloon cells; (c) NASH + Gen8 group showed mild macrovesicular steatosis and mild focal zone 3 inflammation; (d) NASH + Gen16 group maintained the normal structure with only minor changes. Liver sections were stained with hematoxylin and eosin. Images were obtained at ×100 magnification.

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