Evidence-Based Complementary and Alternative Medicine

Research Article

Effects of Hangeshashinto on Growth of Oral Microorganisms

Table 2

Minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of 15 purified compounds.


	MIC/MBC (M)
	1	2	3	4	5	6	7	8	9

Baicalin	—	—	—	—	—	—	—	—	—
Baicalein	—	—	—	25/25	100/100	25/ND	300/300	—	25/25
Wogonin	—	—	—	—	—	—	—	—	—
Acteoside	—	—	—	—	—	—	—	—	—
Berberine	100/100	25/50	50/50	100/100	25/25	100/100	—	25/ND	100/100
Coptisine	50/50	25/50	50/50	100/100	25/25	50/100	—	12.5/ND	100/100
-Shogaol	—	50/50	25/50	25/25	100/100	50/100	—	—	12.5/12.5
-Gingerol	—	—	—	—	—	—	—	—	—
Liquiritin	—	—	—	—	—	—	—	—	—
Glycyrrhizic acid	—	—	—	—	—	—	—	—	—
Ginsenoside Rg1	—	—	—	—	—	—	—	—	—
Ginsenoside Rb1	—	—	—	—	—	—	—	—	—
Corymboside	—	—	—	—	—	—	—	—	—
Homogentisic acid	—	—	—	—	25/25	—	—	—	12.5/12.5
Cyclic AMP	—	—	—	—	—	—	—	—	—

—: not active; ND: not detected.
1: F. nucleatum; 2: P. gingivalis ATCC33277; 3: P. gingivalis 381; 4: P. endodontalis; 5: P. intermedia; 6: P. melaninogenica; 7: T. forsythia; 8: T. denticola; 9: P. asaccharolytica.