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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 516851, 6 pages
Research Article

Function of Nucleus Ventralis Posterior Lateralis Thalami in Acupoint Sensitization Phenomena

1Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie of Dongzhimen, Beijing 100700, China
2Wuhan Integrated TCM and Western Medicine Hospital, 215 Zhongshan Road, Qiaokou District, Wuhan, Hubei 43002, China

Received 20 October 2014; Accepted 11 December 2014

Academic Editor: Jang-Hern Lee

Copyright © 2015 Pei-Jing Rong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral “Zusanli-Shangjuxu” acupoints. The discharge of VPL neurons was response to EA increased after colorectal distension (CRD). The stimulation at “Zusanli-Shangjuxu” acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain. The frequency of neuronal discharge was associated with the pressure gradient of CRD which showed that visceral noxious stimulation may intensify the body’s functional response to stimulation at acupoints.