Gas Chromatography-Mass Spectrometry Analysis of Ulva fasciata (Green Seaweed) Extract and Evaluation of Its Cytoprotective and Antigenotoxic Effects

Table 3

Effects of Ulva fasciata extract on micronucleus assay in Balb/C male mice.

Group (mg/kg)	IC	MN/PCE
Negative control	10.8 ± 0.28	4.3 ± 0.8
Vehicle control	2.1 ± 0.47	6.6 ± 2.6
Benzo(a)pyrene only	2.23 ± 0.75	15.3 ± 2.6
Benzo(a)pyrene + Ulva (50 mg/kg)	2.48 ± 0.50	7.9 ± 1.9
Benzo(a)pyrene + Ulva (100 mg/kg)	1.88 ± 0.25	5.3 ± 1.4
Benzo(a)pyrene + Ulva (250 mg/kg)	2.63 ± 0.47	5.15 ± 0.65

MN: micronucleus; PCE: polychromatic erythrocytes; 2000 cells/animal were examined; IC: cytotoxicity index: polychromatic erythrocytes/normochromatic erythrocytes; ; comparisons between treated groups with the extract plus PB and the control group treated with BP only (Dunnett’s test).