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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 521584, 6 pages
Review Article

Resistance to Antibiotics and Antifungal Medicinal Products: Can Complementary and Alternative Medicine Help Solve the Problem in Common Infection Diseases? The Introduction of a Dutch Research Consortium

1University of Applied Sciences, 2333 CK Leiden, Netherlands
2Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK
3Department of Healthcare and Nutrition, Louis Bolk Institute, 2972 LA Driebergen, Netherlands
4Department of Health Sciences, Mid Sweden University, 871 31 Sundsvall, Sweden
5National Information and Knowledge Centre on Integrative Medicine (NIKIM), Amsterdam, Netherlands
6Naturalis Biodiversity Center, 2333 CR Leiden, Netherlands

Received 29 June 2015; Accepted 25 August 2015

Academic Editor: Cheryl Hawk

Copyright © 2015 Esther T. Kok et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The increase of antibiotic resistance worldwide, rising numbers of deaths and costs associated with this, and the fact that hardly any new antimicrobial drugs have been developed during the last decade have increased the interest in Complementary and Alternative Medicine (CAM) therapeutic interventions, if proven safe and effective. Observational studies on clinical CAM practices demonstrate positive effects of treatment of infections with CAM therapies (clinical effects, patient satisfaction) in combination with small percentages of antibiotics prescription. However, Cochrane reviews and other studies demonstrate that in most instances the quality of clinical trials on CAM treatment of infections is currently too low to provide sufficient evidence. Therefore a Dutch consortium on (in vitro and clinical) scientific research on CAM and antibiotic resistance has been formed. The aim and objective of the consortium is to establish an enduring partnership and to develop expertise to further develop and investigate safe and effective CAM treatments for infectious diseases of humans (and animals). A first ongoing project on the development of safe and effective biobased CAM antimycotics in women with (recurrent) vaginal candidiasis infection is introduced.