Catalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans

Figure 6

Effects of catalpol on the body movement and lipofuscin accumulation in wild-type N2 nematodes. (a) Body movement of worms were counted under a dissecting microscope for 1 min. (b) Fluorescence intensity of lipofuscin and autofluorescence image worms on the 8th day of adulthood. The fluorescence intensity was quantified using ImageJ software by determining average pixel intensity. Mean fluorescence intensity of lipofuscin was represented as mean ± S.E.M. of values from 18-19 animals per each experiment (). Differences compared to the control were considered significant at and by one-way ANOVA.

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