Bacopa monnieri Extract (CDRI-08) Modulates the NMDA Receptor Subunits and nNOS-Apoptosis Axis in Cerebellum of Hepatic Encephalopathy Rats
Expression profile of Bcl2 ((a) and (b)) and Bax ((c) and (d)) in cerebellum of the CLF and BM extract treated CLF rats. Western blot analysis of Bcl2 and Bax was performed as described in the text of methods. The level of β-actin was probed as the loading control. In panels (b), (d), and (e), normalized densitometric values of Bcl2/β-actin, Bax/β-actin, and Bcl2/Bax ratio, respectively, have been presented as mean ± SD from three western blot repeats. , ; (control versus CLF rats) #, ##; (CLF versus CLF + BM rats). C: control, CLF: chronic liver failure, CLF + BM: chronic liver failure + Bacopa monnieri extract.