Research Article
Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study
Table 1
Demographic characteristics and comorbidity in patients with and without dermatitis.
| Variables | Dermatitis | value† | No | Yes | () | () | | % | | % |
| Sex | | | | | | Female | 136734 | 58.13 | 136734 | 58.13 | 0.99 | Male | 98486 | 41.87 | 98486 | 41.87 | | Age, years | | | | | | 20–39 | 118623 | 50.43 | 118623 | 50.43 | 0.99 | 40–49 | 51025 | 21.69 | 51025 | 21.69 | | 50–59 | 31596 | 13.43 | 31596 | 13.43 | | ≥60 | 33976 | 14.44 | 33976 | 14.44 | | Mean (SD)† | 41.47 ± 15.92 | 41.93 ± 15.52 |
<0.0001 | Comorbidity | | | | | | Asthma | 9394 | 3.99 | 14123 | 6.00 | <0.0001 | Allergic rhinitis | 21178 | 9.00 | 33243 | 14.13 | <0.0001 | Urticaria | 11167 | 4.75 | 26983 | 11.47 | <0.0001 | Diabetes mellitus, DM | 14864 | 6.32 | 20171 | 8.58 | <0.0001 | Hypertension | 32216 | 13.70 | 40360 | 17.16 | <0.0001 | Hyperlipidemia | 14819 | 6.30 | 21579 | 9.17 | <0.0001 | Atrial fibrillation, AF | 625 | 0.27 | 700 | 0.30 | 0.0391 | Treatment | | | | | | TCM (excluded acupuncture) | 183949 | 78.20 | 207890 | 88.38 | <0.0001 | Systemic corticosteroid | 160541 | 68.25 | 206402 | 87.75 | <0.0001 | Dexamethasone | 103693 | 44.08 | 146470 | 62.27 | <0.0001 | Methyl prednisolone | 35995 | 15.30 | 62122 | 26.41 | <0.0001 | Prednisolone | 128167 | 54.49 | 182906 | 77.76 | <0.0001 | Treatment (new) | | | | | | Non-TCM and nonsystemic steroid | 25312 | 10.76 | 5507 | 2.34 | <0.0001 | Only TCM | 49367 | 20.99 | 23311 | 9.91 | | Only systemic steroid | 25959 | 11.04 | 21823 | 9.28 | | TCM and systemic steroid | 134582 | 57.22 | 184579 | 78.47 | | Outcome | | | | | | Stroke | 10006 | 4.25 | 13079 | 5.56 | <0.0001 | Hemorrhagic stroke | 1543 | 0.66 | 1463 | 0.62 | 0.1432 | Ischemic stroke | 9277 | 3.94 | 12450 | 5.29 | <0.0001 |
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Chi-square test; †two-sample -test.
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