In Vitro and In Vivo Anticancer Activity of Root Extracts of Sansevieria liberica Gerome and Labroy (Agavaceae)

Table 1

Effects of SL extracts against Sarcoma-180 ascites in BALB/c mice.

Treatments	Dose (mg/kg)	Body weight (g); Day 1	Body weight (g); Day 5	Body weight (g); Day 9	Body weight (g); Day 12	Weight of tumor (g)	Volume of ascitic fluid (mL)	Number of tumor cells (×10^7)	Tumor growth inhibition (%)	Mortality (%)
Normal saline	(0.2 mL/mouse)	21.09 ± 0.56	22.91 ± 0.71	25.18 ± 0.97	24.63 ± 1.49	7.28 ± 0.79	7.47 ± 0.80	178.07 ± 24.98	0	0
5-FU	20	20.00 ± 0.53	20.57 ± 0.69^a	19.43 ± 1.27^b	19.83 ± 1.45^a	0.58 ± 0.37^c	0.53 ± 0.34^c	5.00 ± 3.42^c	97.19	0
SL-A001	100	19.57 ± 0.57^a	21.43 ± 0.72						0	0
SL-A002	80	19.57 ± 0.57^a		18.17 ± 0.70^c	17.80 ± 0.97^b				62.34	0
SL-A003	100	19.86 ± 0.55				2.13 ± 0.75^c	2.13 ± 0.75^c		65.15	42.86
SL-A004	100	20.00 ± 0.53	20.71 ± 0.57^a						23.54	14.29

Values are mean ± SEM (, 11 for control). , , and versus normal saline; , , and versus 5-FU.