In Vitro and In Vivo Anticancer Activity of Root Extracts of Sansevieria liberica Gerome and Labroy (Agavaceae)

Table 2

Effects of SL-A002 extract (100 and 120 mg/kg) against Sarcoma-180 ascites in BALB/c mice.

Treatments	Dose (mg/kg)	Body weight (g); Day 1	Body weight (g); Day 5	Body weight (g); Day 9	Body weight (g); Day 12	Weight of tumor (g)	Volume of ascitic fluid (mL)	Number of tumor cells (×10^7)	Tumor growth inhibition (%)	Mortality (%)
Normal saline	(0.2 mL/mouse)	22.20 ± 0.49	24.00 ± 0.55	26.80 ± 0.49	29.60 ± 0.93	8.74 ± 0.52	8.92 ± 0.51	686.79 ± 54.40	0	0
5-FU	20	21.80 ± 0.58	21.20 ± 0.92^a	19.00 ± 1.26^c	18.00 ± 1.82^c	0.52 ± 0.24^c	0.50 ± 0.22^c	14.00 ± 5.74^c	97.96	0
SL-A002	100	21.80 ± 0.58	21.60 ± 0.51^b	21.20 ± 0.37^c					83.80	0
	120	21.80 ± 0.58	20.40 ± 0.87^b	19.60 ± 0.98^c	20.00 ± 1.82^b	2.85 ± 1.15^b	2.84 ± 1.10^b		89.36	0

Values are mean ± SEM (). , , and versus normal saline; , , and versus 5-FU.