Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal
Table 1
Minimal inhibitory concentration (MIC) of Lavandula stoechas subsp. luisieri and Lavandula pedunculata essential oils and extracts against clinically important fungi species.
Fungi
MIC values (µg/mL)
L. stoechas subsp. luisieri samples
L. pedunculata samples
Controls
EO
-Hex
CH2Cl2
EtOAc
MeOH
H2O
EO
-Hex
CH2Cl2
EtOAc
MeOH
H2O
Amp. B
Ket.
Aspergillus niger
15.5
7.5
31
>100
62.5
>100
>100
>100
>100
>100
>100
>100
0.47
0.064
Candida albicans
>100
>100
62.5
>100
>100
>100
>100
>100
>100
>100
>100
>100
0.125
2
Candida guillermondii
62.5
>100
>100
>100
>100
>100
62.5
62.5
>100
>100
>100
>100
0.064
14
Cryptococcus neoformans
15.5
31
31
31
62.5
62.5
15.5
31
15.5
15.5
15.5
62.5
0.125
6
Rhodotorula rubra
>100
>100
>100
31
>100
>100
62.5
62.5
62.5
>100
>100
>100
0.094
2
Saccharomyces cerevisiae
31
62.5
62.5
62.5
31
62.5
>100
31
31
>100
>100
62.5
0.016
0.5
Trichosporon cutaneum
31
>100
>100
>100
62.5
62.5
62.5
31
31
>100
>100
>100
0.25
0.2
All the tested extracts were considered inactive against Candida dubliniensis, Candida glabrata, Candida kruzei, Candida parapsilosis, and Candida tropicalis (MIC values >100 g/mL). Positive controls: Amp. B: amphotericin B; Ket: ketoconazole. EO: essential oil; -Hex: -hexane; CH2Cl2: dichloromethane; EtOAc: ethyl acetate; MeOH: methanol; H2O: water.
