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Study ID | Source of participants | Sample size (I/C) | Age (years, I/C) | Sex (M/F) | Intervention | Control | Treatment duration (week or month) | Outcomes |
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Pan 2012 [17] | Outpatients and inpatients | I: 30 C: 30 | I: 66.5 ± 4.5 (skewed distribution) C: 67 ± 6.25 (Skewed distribution) | NR | Tian ma shu xin granule, 150 mL bid | Amlodipine besylate tablet, 5 mg qd | 4 w | 24 hCV, dCV, nCV 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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Ma 2013 [18] | Outpatients and inpatients | I: 20 C: 20 | I: 49.00 ± 11.82 C: 55.10 ± 10.44 | 21/19 | Qian yang yu yin granule, 10 g tid | Combined felodipine with enalapril to control blood pressure below 140/90 mmHg. felodipine, 5 mg/d, enalapril 10 mg/d, dose adjustment if blood pressure is above 140/90 mmHg | 8 w | 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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Liang 2007 [19] | Outpatients and inpatients | I: 31 C: 30 | I: 50.39 ± 8.00 C: 51.60 ± 7.07 | 36/25 | Qin dan capsule, 1.75 g tid | Enalapril maleate tablet, 5 mg bid group | 8 w | dSD, nSD 24 hBP, The nighttime blood pressure decrease rate |
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Shi 2011 [20] | Outpatients and inpatients | I: 20 C: 20 | I: 74.25 ± 8.42 C: 73.05 ± 9.32 | 33/7 | Sang ji wen dan decoction, one packet, bid | Amlodipine besylate tablet, 5 mg qd, group | 4 w | 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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Wang 2011 [21] | Outpatients | I: 70 C: 68 | I: 52.1 ± 9.3 C: 50.3 ± 8.9 | 73/65 | Songling Xuemaikang capsule, 1.5 g, tid | Amlodipine besylate tablet, 5 mg qd | 4 w | dSD, nSD 24 hBP |
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Kang and Fan 2013 [22] | Outpatients and inpatients
| I: 60 C: 58 | I: 67 ± 10 C: 66 ± 9 | 72/46 | Xian dan tong mai decoction, one packet, bid | Amlodipine besylate tablet, 5 mg qd | 4 w | 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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Ma et al. 2013 [23] | Outpatients | I: 41 C: 37 | I: 50.42 ± 4.34 C: 51.45 ± 4.70 | NR | Xiang tian ma decoction, one packet, bid | Benazepril, 10 mg qd | 8 w | 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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Li 2012 [24] | NR | I: 54 C: 56 | I: NR C: NR | NR | Xuezhikang capsule 600 mg, bid | A combination of ACEI and CCB as basic treatment, drug adjustment according to the circumstances | 6 m | 24 hSD 24 hBP |
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Ji and Han 2011 [25] | Outpatients and patients in hospital | I: 80 C: 80 | I: 53.3 ± 11.08 C: 56.7 ± 11.61 | 90/70 | Yang xue qing nao granule, one packet, tid | Conventional antihypertensive drugs | 12 w | dSD, nSD 24 hBP, dBP, nBP, Circadian rhythm of blood pressure |
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Zhang et al. 2012 [26] | Outpatients and patients in hospital | I: 40 C: 40 | I: NR C: NR | NR | Yin gan jing decoction, one packet, bid | Amlodipine besylate tablet, 5 mg qd, group | 1 m | 24 hSD, 24 hBP, dBP, nBP, trough-to-peak ratios, 24 h smoothness index (SI) The nighttime blood pressure decreased rate |
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Yan 2008 [27] | Outpatients and patients in hospital | I: 30 C: 28 | I: 61.54 ± 6.53 C: 60.94 ± 8.01 | 30/28 | Tiao ping kang tablet 4 tablets, tid | Nifedipine controlled released Tablets, 30 mg, qd | 4 w | 24 hSD, dSD, nSD 24 hBP, dBP, nBP, trough-to-peak ratios, Circadian rhythm of blood pressure, lowering blood pressure load value, morning blood pressure, stationarity index pulse pressure, pulse pressure drop rate |
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Liang 2011 [28] | NR | I: 35 C: 35 | I: 61.3 ± 5.38 C: 61.7 ± 4.76 | 32/38 | Gou teng si wu decoction, one packet, bid | Levamlodipine besylate tablets, 2.5 mg, qd | 4 w | 24 hSD, 24 hBP, 24 h blood pressure load, 24 h trough-to-peak ratios the nighttime blood pressure decrease rate |
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Chen 2012 [29] | Outpatients | I: 45 C: 45 | I: NR C: NR | NR | Qing xuan granule, one packet, bid | Amlodipine besylate tablet, 5 mg qd, group | 8 w | 24 hCV, dCV, nCV 24 hSD, dSD, nSD 24 hBP, dBP, nBP |
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