Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4

<div>Aquaporin 4 (AQP4) expression in the ipsilateral hippocampus by western blot. CIR, cerebral ischemia/reperfusion group; Sham, sham-operated group; SHD, Sanhua decoction-treated group; SHD + RNAi, Sanhua decoction plus AQP4-siRNA-treated group; SHD + Vec, Sanhua decoction plus vector-treated group; RNAi, AQP4-siRNA-treated group; Vector, vector-treated group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4 