Effect of Sterols Isolated from Myrtillocactus geometrizans on Growth Inhibition of Colon and Breast Cancer Cells

Table 1

Cytotoxicity (IC₅₀) of peniocerol and macdougallin in HCT-15 and MCF-7 cancer cells.

Compound	Human cancer cell lines	IC50 value (μM)	Incubation time (hour)
Peniocerol	HCT-15	41.66 ± 0.41	24
		28.85 ± 0.60	48
	MCF-7	48.17 ± 0.35	24
		21.77 ± 0.39	48
Macdougallin	HCT-15	37.67 ± 0.76	24
		33.71 ± 0.84	48
	MCF-7	31.83 ± 1.06	24
		28.15 ± 0.54	48
Doxorubicin (DOX)	HCT-15	0.36 ± 0.03	24
		0.16 ± 0.02	48
	MCF-7	0.37 ± 0.02	24
		0.28 ± 0.01	48

HCT-15: colorectal adenocarcinoma. MCF-7: breast adenocarcinoma.
Values are expressed as mean ± S.D of three independent experiments, each made in triplicate.