Research Article

Effect of Sterols Isolated from Myrtillocactus geometrizans on Growth Inhibition of Colon and Breast Cancer Cells

Table 2

Percentage of apoptosis induced by peniocerol or macdougallin in HCT-15 cell line.

TreatmentPercentage of apoptosis (%)

(A) Control, HCT-15, 24 h7.14 ± 1.13% (EA)
0.24 ± 0.11% (LA)

(B) Peniocerol 40 μM, 24 h51.96 ± 5.54% (EA)
0.11 ± 0.06% (LA)

(C) Peniocerol 60 μM, 24 h73.36 ± 4.20% (EA)
14.60 ± 2.53% (LA)

(D) Macdougallin 40 μM, 24 h63.30 ± 0.42% (EA)
1.39 ± 0.22% (LA)

(E) Macdougallin 60 μM, 24 h77.63 ± 2.81% (EA)
0.04 ± 0.05% (LA)

EA: early apoptosis, LA: late apoptosis.
Values are expressed as mean + S.D. of three independent experiments, each made in triplicate.