(a) 2-OG
(b) Cit
(c) Hipp
(d) Succ
(e) Tau
(f) TMAO
Figure 3: Abundance of selected metabolites was obtained by measuring the integral of a single, resolved resonance from each metabolite in 1H-NMR of urine from rats after treatment with matrine. (a) 2-oxoglutarate, (b) citrate, (c) hippurate, (d) succinate, (e) taurine, (f) trimethylamine N-oxide. White bar: control group, gray bar: low dose group, striped bar: middle dose group, and black bar: high dose group. Data presented in this figure were mean ± SD . Asterisks indicate statistically significant differences between control and treated cells (, ).