Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 3

Research Article

Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo

Figure 3

Abundance of selected metabolites was obtained by measuring the integral of a single, resolved resonance from each metabolite in 1H-NMR of urine from rats after treatment with matrine. (a) 2-oxoglutarate, (b) citrate, (c) hippurate, (d) succinate, (e) taurine, (f) trimethylamine N-oxide. White bar: control group, gray bar: low dose group, striped bar: middle dose group, and black bar: high dose group. Data presented in this figure were mean ± SD . Asterisks indicate statistically significant differences between control and treated cells (, ).
(a) 2-OG
(b) Cit
(c) Hipp
(d) Succ
(e) Tau
(f) TMAO

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