Toxic Markers of Matrine Determined Using <sup><b>1</b></sup>H-NMR-Based Metabolomics in Cultured Cells <i>In Vitro</i> and Rats <i>In Vivo</i>

<div>Abundance of selected metabolites was obtained by measuring the integral of a single, resolved resonance from each metabolite in <sup>1</sup>H-NMR of HepG2 cells upon exposure time. (a) Alanine, (b) choline, (c) glutathione, (d) lactate, (e) phosphocholine, (f) taurine, (g) cholesterol, (h) fatty acid, and (i) unsaturated fatty acid. White bar: control group, gray bar: low dose group, striped bar: middle dose group, and black bar: high dose group. 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Toxic Markers of Matrine Determined Using <sup><b>1</b></sup>H-NMR-Based Metabolomics in Cultured Cells <i>In Vitro</i> and Rats <i>In Vivo</i> 

Evidence-Based Complementary and Alternative Medicine

Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo

Figure 5

Toxic Markers of Matrine Determined Using ¹H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo