Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study

Table 2

ES-SCLC patient characteristics.

Characteristics	Time of CHD treatment (months)
	First phase		Second phase		Total time
	>3 ()	≤3 ()	>7 ()	≤7 ()	>12 ()	<12 ()
Median age (range)	60 (42–75)	62 (47–74)	61 (55–70)	60 (42–74)	61 (47–70)	60 (42–74)
Sex, (%)
Men	11 (73)	11 (85)	10 (77)	11 (79)	11 (73)	11 (85)
Women	4 (27)	2 (15)	3 (23)	3 (21)	4 (27)	2 (15)
Smoking status index, (%)
<400	3 (20)	3 (23)	2 (15)	4 (29)	4 (27)	2 (15)
≥400	9 (60)	8 (62)	9 (69)	7 (50)	9 (60)	8 (62)
No history of smoking	3 (20)	2 (15)	2 (15)	3 (21)	2 (13)	3 (23)
PS, (%)
1	7 (47)	6 (46)	9 (69)	7 (50)	8 (53)	6 (46)
2	8 (53)	7 (54)	4 (31)	7 (50)	7 (47)	7 (54)
Site of metastasis, (%)
Lung	6 (40)	9 (69)	7 (54)	8 (57)	7 (54)	8 (61)
Distant lymph nodes	15 (100)	13 (100)	13 (100)	14 (100)	15 (100)	13 (100)
Bone	2 (13)	—	1 (8)	1 (7)	1 (7)	1 (8)
Peritoneum	1 (7)	1 (8)	1 (8)	1 (7)	2 (13)	—
Pleura	1 (7)	—	1 (8)	—	1 (7)	—
Hydrothorax	1 (7)	—	1 (8)	—	1 (7)	—
Concomitant diseases, (%)
Diabetes	5 (33)	3 (23)	4 (31)	4 (29)	8 (53)	3 (23)
Hypertension	1 (7)	3 (23)	3 (23)	1 (7)	2 (13)	2 (15)
Heart disease	1 (7)	1 (8)	2 (15)	—	2 (13)	—
Effectiveness of chemotherapy response, (%)
Complete response	2 (13)	2 (14)	4 (31)	—	4 (27)	—
Partial response	7 (47)	8 (62)	7 (54)	7 (50)	11 (73)	4 (31)
Stable disease	4 (27)	5 (38)	2 (15)	7 (50)	—	9 (69)
Radiotherapy, (%)	7 (47)	8 (62)	6 (46)	9 (64)	7 (47)	8 (61)