Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study
Table 2
ES-SCLC patient characteristics.
Characteristics
Time of CHD treatment (months)
First phase
Second phase
Total time
>3 ()
≤3 ()
>7 ()
≤7 ()
>12 ()
<12 ()
Median age (range)
60 (42–75)
62 (47–74)
61 (55–70)
60 (42–74)
61 (47–70)
60 (42–74)
Sex, (%)
Men
11 (73)
11 (85)
10 (77)
11 (79)
11 (73)
11 (85)
Women
4 (27)
2 (15)
3 (23)
3 (21)
4 (27)
2 (15)
Smoking status index, (%)
<400
3 (20)
3 (23)
2 (15)
4 (29)
4 (27)
2 (15)
≥400
9 (60)
8 (62)
9 (69)
7 (50)
9 (60)
8 (62)
No history of smoking
3 (20)
2 (15)
2 (15)
3 (21)
2 (13)
3 (23)
PS, (%)
1
7 (47)
6 (46)
9 (69)
7 (50)
8 (53)
6 (46)
2
8 (53)
7 (54)
4 (31)
7 (50)
7 (47)
7 (54)
Site of metastasis, (%)
Lung
6 (40)
9 (69)
7 (54)
8 (57)
7 (54)
8 (61)
Distant lymph nodes
15 (100)
13 (100)
13 (100)
14 (100)
15 (100)
13 (100)
Bone
2 (13)
—
1 (8)
1 (7)
1 (7)
1 (8)
Peritoneum
1 (7)
1 (8)
1 (8)
1 (7)
2 (13)
—
Pleura
1 (7)
—
1 (8)
—
1 (7)
—
Hydrothorax
1 (7)
—
1 (8)
—
1 (7)
—
Concomitant diseases, (%)
Diabetes
5 (33)
3 (23)
4 (31)
4 (29)
8 (53)
3 (23)
Hypertension
1 (7)
3 (23)
3 (23)
1 (7)
2 (13)
2 (15)
Heart disease
1 (7)
1 (8)
2 (15)
—
2 (13)
—
Effectiveness of chemotherapy response, (%)
Complete response
2 (13)
2 (14)
4 (31)
—
4 (27)
—
Partial response
7 (47)
8 (62)
7 (54)
7 (50)
11 (73)
4 (31)
Stable disease
4 (27)
5 (38)
2 (15)
7 (50)
—
9 (69)
Radiotherapy, (%)
7 (47)
8 (62)
6 (46)
9 (64)
7 (47)
8 (61)
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