(a)
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Figure 2: Partial hepatectomy is a delayed cell cycle physiological response. (a) Quantification of western blot densitometry analysis of G1 phase checkpoint proteins, cyclin D1 and pRb, expression levels in Sham, PHx, and silymarin (Sm) treatment partial hepatectomy at 6 hrs, 24 hrs, and 72 hrs. All data are presented as means SEM, , as compared with the corresponding sham group. , , as compared with the corresponding PHx. as compared with 6 hrs sham group. as compared with 24 hrs sham group. as compared with 6 hrs PHx group. as compared with 24 hrs PHx group. (b) Quantification of western blot densitometry analysis of S phase checkpoint proteins, cyclin E and E2F, expression levels in Sham, PHx, and silymarin (Sm) treatment partial hepatectomy at 6 hrs, 24 hrs, and 72 hrs. All data are presented as means SEM; , as compared with the corresponding sham group. , as compared with the corresponding PHx. , as compared with 6 hrs sham group. as compared with 24 hrs sham group. , , as compared with 6 hrs PHx group. , as compared with 24 hrs PHx group. (c) Representative cell cycle in sham and PHx at 6 hrs, 24 hrs, and 72 hrs three different times.