AP-1-Targeting Anti-Inflammatory Activity of the Methanolic Extract of Persicaria chinensis

Figure 2

Effect of Pc-ME on the reporter gene assay. The promoter binding activity of the transcription factor AP-1 was analyzed using a reporter gene assay in HEK293 cells transfected with plasmid constructs AP-1-Luc (1 μg/mL) or β-gal (as a transfection control) with 1 μg/mL of MyD88 (a) or TRIF (b) and 100 nM PMA (c) in the presence of Pc-ME. Luciferase activity was measured using a luminometer. compared with control.

(a)

(b)

(c)