Research Article
Effects of Green Tea Extracts on the Pharmacokinetics of Quetiapine in Rats
Table 1
Pharmacokinetic parameters of QUE in rats after administration of a single oral dose of 25.0 mg/kg with and without GTE (175 mg/kg) (mean ± SE, ).
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Significant difference from “QUE alone” group with -test, * ≤ 0.05; : maximum plasma concentration; : time to maximum plasma concentration; AUC: area under curve; : elimination rate constant; : elimination half-life; CL: clearance; MRT: mean residence time. |