Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 615384, 9 pages
http://dx.doi.org/10.1155/2015/615384
Review Article

Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain

1Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia
2Department of Neurology, Boston University School of Medicine and Framingham Heart Study, Boston, MA 02118, USA

Received 19 January 2015; Revised 26 March 2015; Accepted 10 April 2015

Academic Editor: Abid Hamid

Copyright © 2015 Tamara Simpson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Sakia Ferdousy, Md Atiar Rahman, Md Mamun Al-Amin, Jannatul Aklima, and J. M. Kamirul Hasan Chowdhury, “Antioxidative and neuroprotective effects of Leea macrophylla methanol root extracts on diazepam-induced memory impairment in amnesic Wistar albino rat,” Clinical Phytoscience, vol. 2, no. 1, 2016. View at Publisher · View at Google Scholar
  • Tony L Brown, “Alzheimer’s Disease Prevention and Treatment Using Herbal Agents,” Journal of Analytical & Pharmaceutical Research, vol. 2, no. 4, 2016. View at Publisher · View at Google Scholar
  • Ari Barzilai, Björn Schumacher, and Yosef Shiloh, “Genome Instability: Linking Ageing and Brain Degeneration,” Mechanisms of Ageing and Development, 2016. View at Publisher · View at Google Scholar
  • Rishi K. Vishwakarma, Uma Kumari, and Bashir M. Khan, “Memory Booster Plant Bacopa monniera (Brahmi): Biotechnology and Molecular Aspects of Bacoside Biosynthesis,” Medicinal Plants - Recent Advances in Research and Development, pp. 167–189, 2016. View at Publisher · View at Google Scholar
  • Surya Prakash Pandey, and S. Prasad, “Diabetes Mellitus Type 2 Induces Brain Aging and Memory Impairment in Mice: Neuroprotective Effects of Bacopa monnieri Extract,” Topics in Biomedical Gerontology, pp. 335–355, 2016. View at Publisher · View at Google Scholar
  • Wilfried Dimpfel, Leonie Schombert, and Andreas Biller, “Psychophysiological Effects of <i>Sideritis</i> and <i>Bacopa</i> Extract and Three Combinations Thereof—A Quantitative EEG Study in Subjects Suffering from Mild Cognitive Impairment (MCI),” Advances in Alzheimer's Disease, vol. 05, no. 01, pp. 1–22, 2016. View at Publisher · View at Google Scholar
  • Chunlei Zhou, Lan Zhao, Jian Zheng, Kai Wang, Haixia Deng, Ping Liu, Li Chen, and Hong Mu, “MicroRNA-144 modulates oxidative stress tolerance in SH-SY5Y cells by regulating nuclear factor erythroid 2-related factor 2-glutathione axis,” Neuroscience Letters, 2017. View at Publisher · View at Google Scholar
  • Kaustubh Suresh Chaudhari, Nishant R. Tiwari, Rakesh R. Tiwari, and Rohan S. Sharma, “Neurocognitive effect of nootropic drug Brahmi (Bacopa monnieri) in Alzheimer’s disease,” Annals of Neurosciences, vol. 24, no. 2, pp. 111–122, 2017. View at Publisher · View at Google Scholar
  • Gaurav Bhatia, Vikram Dhuna, Kshitija Dhuna, Manpreet Kaur, and Jatinder Singh, “Bacopa monnieri extracts prevent hydrogen peroxide-induced oxidative damage in a cellular model of neuroblastoma IMR32 cells,” Chinese Journal of Natural Medicines, vol. 15, no. 11, pp. 834–846, 2017. View at Publisher · View at Google Scholar
  • Shishir Kumar Patel, Shilpi Singh, and Shio Kumar Singh, “Standardized extract of Bacopa monnieri (CDRI-08): Effect on germ cell dynamics and possible mechanisms of its beneficial action on spermatogenesis and sperm quality in male mice,” Biochemical and Biophysical Research Communications, 2017. View at Publisher · View at Google Scholar
  • Noushin Nikray, Isaac Karimi, Zahraminoosh Siavashhaghighi, Lora A. Becker, and Mohammad Mehdi Mofatteh, “An effort toward molecular biology of food deprivation induced food hoarding in gonadectomized NMRI mouse model: focus on neural oxidative status,” BMC Neuroscience, vol. 19, no. 1, 2018. View at Publisher · View at Google Scholar
  • Saurabh Srivastav, Mahino Fatima, and Amal Chandra Mondal, “Bacopa monnieri alleviates paraquat induced toxicity in Drosophila by inhibiting jnk mediated apoptosis through improved mitochondrial function and redox stabilization,” Neurochemistry International, 2018. View at Publisher · View at Google Scholar
  • Niki Chondrogianni, and Nikoletta Papaevgeniou, “Anti-aging and anti-aggregation properties of polyphenolic compounds in C. Elegans,” Current Pharmaceutical Design, vol. 24, no. 19, pp. 2107–2120, 2018. View at Publisher · View at Google Scholar
  • Hang Thi Nguyet Pham, Sinh Viet Phan, Hong Nguyen Tran, Xuyen Thi Phi, Xoan Thi Le, Khoi Minh Nguyen, Hironori Fujiwara, Masanori Yoneyama, Kiyokazu Ogita, Taro Yamaguchi, and Kinzo Matsumoto, “Bacopa monnieri (L.) Ameliorates Cognitive Deficits Caused in a Trimethyltin-Induced Neurotoxicity Model Mice,” Biological and Pharmaceutical Bulletin, vol. 42, no. 8, pp. 1384–1393, 2019. View at Publisher · View at Google Scholar
  • Tamara Simpson, Christina Kure, and Con Stough, “Assessing the Efficacy and Mechanisms of Pycnogenol® on Cognitive Aging From In Vitro Animal and Human Studies,” Frontiers in Pharmacology, vol. 10, 2019. View at Publisher · View at Google Scholar
  • Con Stough, Madeleine Nankivell, David A. Camfield, Naomi L. Perry, Andrew Pipingas, Helen Macpherson, Keith Wesnes, Ruchong Ou, David Hare, Judy de Haan, Geoffrey Head, Peter Lansjoen, Alena Langsjoen, Brendan Tan, Matthew P. Pase, Rebecca King, Renee Rowsell, Oliver Zwalf, Yossi Rathner, Matthew Cooke, and Franklin Rosenfeldt, “CoQ10 and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly,” Frontiers in Aging Neuroscience, vol. 11, 2019. View at Publisher · View at Google Scholar
  • Girdhari Lal Gupta, and Lalit Sharma, “Bacopa monnieri abrogates alcohol abstinence-induced anxiety-like behavior by regulating biochemical and Gabra1, Gabra4, Gabra5 gene expression of GABAA receptor signaling pathway in rats,” Biomedicine & Pharmacotherapy, vol. 111, pp. 1417–1428, 2019. View at Publisher · View at Google Scholar
  • Nasreena Sajjad, Abubakar Wani, Ankita Sharma, Rohaya Ali, Sumaya Hassan, Rabia Hamid, Huma Habib, and Bashir Ahmad Ganai, “Artemisia amygdalina Upregulates Nrf2 and Protects Neurons Against Oxidative Stress in Alzheimer Disease,” Cellular and Molecular Neurobiology, 2019. View at Publisher · View at Google Scholar
  • Neetu Saini, Devinder Singh, and Rajat Sandhir, “Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action,” Metabolic Brain Disease, 2019. View at Publisher · View at Google Scholar
  • Madhuri G S Aithal, and Narayanappa Rajeswari, “Bacoside A Induced Sub-G0 Arrest and Early Apoptosis in Human Glioblastoma Cell Line U-87 MG through Notch Signaling Pathway,” Brain Tumor Research and Treatment, vol. 7, 2019. View at Publisher · View at Google Scholar