Research Article

Evaluation of the Anxiolytic and Antidepressant Activities of the Aqueous Extract from Camellia euphlebia Merr. ex Sealy in Mice

Table 1

Effects of oral administration of CEE (500, 1000, 2000, or 4000 mg/kg) or normal saline (0.4 mL/25 g) on toxic symptoms and mortality in mice.

DrugDose (mg/kg)Mortality (%)Symptoms of toxicity

Saline0None
CEE5000None
CEE10000None
CEE20000Sedation
CEE40000Sedation, hyperventilation

The toxic symptoms include sedation, hypoactivity, loss of appetite, piloerection, convulsion, dizziness, syncope, and hyperventilation.