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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 620383, 13 pages
http://dx.doi.org/10.1155/2015/620383
Research Article

Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 Expression

1Department of Natural Biotechnology, Nanhua University, Sec. 1, No. 55, Nanhua Road, Dalin, Chiayi 62249, Taiwan
2Cardiovascular Center and Department of Anesthesiology, Taichung Veterans General Hospital, Sec. 4, No. 1650 Taiwan Boulevard, Taichung 40705, Taiwan
3Department of Medicine and Cardiovascular Research Center, National Yang-Ming University School of Medicine, Sec. 2, No. 155, Linong Street, Taipei 11221, Taiwan

Received 19 November 2014; Revised 8 January 2015; Accepted 9 January 2015

Academic Editor: Min Li

Copyright © 2015 Yueh-Chiao Yeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Yueh-Chiao Yeh, Tsun-Jui Liu, and Hui-Chin Lai, “Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 Expression,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 620383, 13 pages, 2015. https://doi.org/10.1155/2015/620383.