Antinociceptive Effect of the Essential Oil Obtained from the Leaves of Croton cordiifolius Baill. (Euphorbiaceae) in Mice

Figure 4

Evaluation of the pretreatment with naloxone (2 mg/kg, i.p.) in the effect of C. cordiifolius essential oil (CcEO; 50 and 100 mg/kg, i.p.) and morphine (7.5 mg/kg, i.p.) in the acetic acid induced writhing test. Results are expressed as mean ± SEM () with significance level set at . When compared to the vehicle group; ^awhen compared to morphine group.