Neurosupportive Role of Vanillin, a Natural Phenolic Compound, on Rotenone Induced Neurotoxicity in SH-SY5Y Neuroblastoma Cells

Figure 4

(a) Vanillin reduced ROS formation as stained by 1 μM CM-H2 DCFDA. (a) Photomicrograph showing the preventive effect of vanillin (100 nM) against rotenone induced ROS generation. (A) Control, (B) rotenone, (C) vanillin + rotenone, and (D) vanillin. (b) Rotenone (100 nM) treatment significantly increased the levels of ROS as compared to control cells, while vanillin (100 nM) pretreatment significantly decreased the levels of ROS as compared to rotenone alone treated cells. Values are given as mean ± SD of four independent experiments in each group. compared to control and compared to rotenone group (DMRT).

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