Research Article

Antifungal Properties of Crude Extracts, Fractions, and Purified Compounds from Bark of Curatella americana L. (Dilleniaceae) against Candida Species

Figure 1

Isobologram showing synergic interaction between F2#5 and F2#6 against Candida albicans. FIC = 0.28. The dotted lines indicate a theoretical additive activity. The measured lines yielded a highly concave curve, a characteristic of strong drug synergism (fractional inhibitory concentration index ≤0.5).