Curcumin Pharmacokinetic and Pharmacodynamic Evidences in Streptozotocin-Diabetic Rats Support the Antidiabetic Activity to Be via Metabolite(s)

Figure 3

Oral glucose tolerance of normal and STZ-diabetic rats treated with curcumin incorporated in yoghurt. Glycemia levels before () and after glucose overload in rats treated for 1 day ((a) diabetic; (b) normal) and for 15 days ((c) diabetic; (d) normal) with curcumin. The insets represent the AUC values (g/dL/120 min). Values are expressed as means ± SEM, -8 per group. Differences between groups were analyzed with one-way ANOVA followed by Student-Newman-Keuls test (). #: differences with NYOG and NC90; : differences with DYOG.

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