Ferulic Acid Induces Th1 Responses by Modulating the Function of Dendritic Cells and Ameliorates Th2-Mediated Allergic Airway Inflammation in Mice

Figure 8

Effect of ferulic acid on the cytokine profile of OVA-restimulated splenocytes. Splenocytes (10⁷ cells/mL) from FA-treated and control groups were stimulated with 50 μg/mL OVA in 24-well plates, and culture supernatants were collected after 72 h. Levels of cytokine production of IL-4, IL-5, IL-13, IFN-γ, TNF-α, IL-1β, and IL-6 were analyzed by an ELISA. Results are expressed as the mean ± SEM ( in each group). , , and versus the PC group.