A Lindera obtusiloba Extract Blocks Calcium-/Phosphate-Induced Transdifferentiation and Calcification of Vascular Smooth Muscle Cells and Interferes with Matrix Metalloproteinase-2 and Metalloproteinase-9 and NF-B

Figure 4

Effects of LOE on Ca/P-induced mRNA expressions of osterix, osteocalcin, α-SMA, and SM22α. The mRNA expressions of osterix and osteocalcin () (a) and of α-SMA and SM22α () (b) in murine VSMC were determined by RT-PCR. The expression pattern after 24 h of stimulation is shown (means SD; significant; ; ; ).

(a)

(b)