Research Article

Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman

Table 2

The sensitivity patterns, minimum inhibitory concentrations (MICs), and minimum fungicidal concentrations (MFCs) exhibited by Alchornea laxiflora crude leaf extract against tested fungal isolates.

Fungal isolatesZones of inhibition
A. laxiflora
(35 mg/mL)
Nystatin
(1 mg/mL)
MIC 
(mg/mL)
MFC 
(mg/mL)

Aspergillus niger 22 ± 0.0024 ± 1.5535.00ND
Aspergillus fumigatus 17 ± 0.5025 ± 0.5635.00ND
Aspergillus glaucus 17 ± 0.1022 ± 0.0017.5035.00
Fusarium species017 ± 0.00NDND
Penicillium expansum 12 ± 0.0020 ± 0.5517.5035.00
Alternaria species21 ± 0.5016 ± 1.5535.00ND
Trichophyton tonsurans 23 ± 0.5031 ± 2.002.198.75
Trichophyton interdigitale 17 ± 1.0029 ± 2.0017.5035.00
Penicillium camemberti 17 ± 0.0021 ± 1.0017.5035.00
Trichophyton mentagrophytes 23 ± 0.5030 ± 1.0017.5035.00
Trichoderma species (nonpathogen)13 ± 0.5015 ± 0.008.7517.50
Aspergillus flavus 16 ± 0.0020 ± 1.5535.00ND
Scopulariopsis brevicaulis 18 ± 0.5022 ± 1.2235.00ND
Penicillium italicum 14 ± 0.0526 ± 1.528.7535.00
Trichophyton rubrum 013 ± 1.50NDND
Candida albicans 18 ± 0.5028 ± 0.5535.00ND
Candida pseudotropicalis 18 ± 0.0027 ± 1.518.7517.50

: mean of three replicates; MIC: minimum inhibitory concentration; MFC: minimum fungicidal concentration; 0: no activity; Nystatin: positive control; ND: not determined.