Effects of Soothing Liver and Invigorating Spleen Recipes on the IKK-NF-B Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats

Table 2

Expression of IKKβ and NF-κB mRNA in KCs (, = 6).

	2^−ΔΔCT IKKβ Rel. to control	2^−ΔΔCT NF-κB p65Rel. to control
Normal	1 (0.25–4.09)	1 (0.39–2.65)
Model	20.56 (4.56–34.05)^a	16.29 (2.77–48.16)^a
L-SLG	17.99 (1.89–30.69)	14.43 (2.33–31.12)
H-SLG	14.34 (3.51–23.43)^b	10.39 (2.15–22.31)^b
L-ISG	15.63 (7.31–28.05)	12.07 (7.06–15.78)
H-ISG	10.32 (3.83–23.91)^c	9.15 (4.43–27.10)^c
L-IG	12.09 (4.75–20.11)^b	9.85 (2.56–18.90)^b
H-IG	6.55 (1.80–14.83)^cd	4.76 (0.55–12.47)^cd

Expression of IKKβ and NF-κB mRNA in KCs was determined by Q-PCR. Rats were fed with normal chow diet or HFD with or without CSS and SLBZS for 26 weeks. The values were expressed as mean ± S.E.M. of 6 rats per group. versus normal group; , versus model group, versus H-ISG and L-IG group.