Ergosterol Alleviates Kidney Injury in Streptozotocin-Induced Diabetic Mice

Figure 5

Effect of ERG on PI3K/Akt/NF-κB pathway-related pathway. Mice were intraperitoneally injected with 135 mg/kg of STZ. ALL (5 mg/kg) and ERG (50, 100 mg/kg) were intragastrically treated for consecutive 28 days. Values are expressed as means ± SDs. Compared with control: ; compared with model: , . Compared with STZ + ERG (50 mg/kg) group: . A: control; B: STZ; C: STZ + ALL (5 mg/kg); D: STZ + ERG (50 mg/kg); E: STZ + ERG (100 mg/kg).