Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 704390, 8 pages
http://dx.doi.org/10.1155/2015/704390
Research Article

Xueshuan Xinmaining Tablet Treats Blood Stasis through Regulating the Expression of F13a1, Car1, and Tbxa2r

1Department of Pathogeny Biology, Basic Medical College, Jilin University, Changchun 130021, China
2Departments of Pharmaceutical, Jilin University, Changchun 130021, China
3Department of Cardiology, First Hospital, Jilin University, Changchun 130021, China

Received 22 August 2014; Revised 10 December 2014; Accepted 11 December 2014

Academic Editor: Hubiao Chen

Copyright © 2015 Xiaotian Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Efferth, P. C. H. Li, V. S. B. Konkimalla, and B. Kaina, “From traditional Chinese medicine to rational cancer therapy,” Trends in Molecular Medicine, vol. 13, no. 8, pp. 353–361, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. S.-M. Li, H. Xu, and K.-J. Chen, “The diagnostic criteria of blood-stasis syndrome: considerations for standardization of pattern identification,” Chinese Journal of Integrative Medicine, vol. 20, no. 7, pp. 483–489, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. K.-J. Chen, “Blood stasis syndrome and its treatment with activating blood circulation to remove blood stasis therapy,” Chinese Journal of Integrative Medicine, vol. 18, no. 12, pp. 891–896, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. D.-Z. Shi, H. Xu, H.-J. Yin, J.-C. Zhang, and K.-J. Chen, “Combination and transformation of toxin and blood stasis in etiopathogenesis of thrombotic cerebrocardiovascular diseases,” Zhong Xi Yi Jie He Xue Bao, vol. 6, no. 11, pp. 1105–1108, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. L. Wang, G.-B. Zhou, P. Liu et al., “Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 12, pp. 4826–4831, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. M. S. Chow and Y. Huang, “Utilizing chinese medicine to improve cancer therapy-fiction or reality?” Current Drug Discovery Technologies, vol. 7, article 1, 2010. View at Google Scholar
  7. X. Zhao, D. Sui, X. Yu, S. Qu, and H. Xu, “Protective effect and mechanism of XueshuanXinmaining tablets on acute myocardial infarction,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 6, pp. 177–179, 2008. View at Google Scholar
  8. J. Liu, S. Qu, X. Yu, X. Huali, and S. Dayuan, “The protective effect of of Xueshuan Xinmaining tablets on experimental cerebral ischemia in rats,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 9, pp. 333–334, 2011. View at Google Scholar
  9. Z. Wen, Z. Wang, S. Wang et al., “Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression microarray and connectivity map,” PLoS ONE, vol. 6, no. 3, Article ID e18278, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Chavan, K. Joshi, and B. Patwardhan, “DNA microarrays in herbal drug research,” Evidence-Based Complementary and Alternative Medicine, vol. 3, no. 4, pp. 447–457, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. J. X. Kang, J. Liu, J. Wang, C. He, and F. P. Li, “The extract of huanglian, a medicinal herb, induces cell growth arrest and apoptosis by upregulation of interferon-β and TNF-α in human breast cancer cells,” Carcinogenesis, vol. 26, no. 11, pp. 1934–1939, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. E. Chan, M. Tan, J. Xin, S. Sudarsanam, and D. E. Johnson, “Interactions between traditional Chinese medicines and Western therapeutics,” Current Opinion in Drug Discovery and Development, vol. 13, no. 1, pp. 50–65, 2010. View at Google Scholar · View at Scopus
  13. J. Zhang, G. Zuo, Q. Bai, Y. Wang, R. Yang, and J. Qiu, “Microarray expression profiling of Yersinia pestis in response to berberine,” Planta Medica, vol. 75, no. 4, pp. 396–398, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. C.-Y. Wang, V. Staniforth, M.-T. Chiao et al., “Genomics and proteomics of immune modulatory effects of a butanol fraction of Echinacea purpurea in human dendritic cells,” BMC Genomics, vol. 9, article 479, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. W.-Y. Cheng, S.-L. Wu, C.-Y. Hsiang et al., “Relationship between San-Huang-Xie-Xin-Tang and its herbal components on the gene expression profiles in HepG2 cells,” The American Journal of Chinese Medicine, vol. 36, no. 4, pp. 783–797, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. N.-S. Yang, L.-F. Shyur, C.-H. Chen, S.-Y. Wang, and C.-M. Tzeng, “Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cells,” Journal of Biomedical Science, vol. 11, no. 3, pp. 418–422, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Zhang, B. Huang, Y. Zhao et al., “BNC protects H9c2 cardiomyoblasts from H2O2-induced oxidative injury through ERK1/2 signaling pathway,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 802784, 12 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. M.-W. Huang, H. Wang, W.-J. Zhong, X.-Y. Wu, and H. Chen, “Chinese herbal medicine Naoxintong capsule combined with dual antiplatelet therapy in a rat model of coronary microembolization induced by homologous microthrombi,” Journal of Chinese Integrative Medicine, vol. 9, no. 1, pp. 38–48, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Wang, W.-J. Zhong, M.-W. Huang, X.-Y. Wu, and H. Chen, “Efficacy of dual antiplatelet therapy combined with Naoxintong Capsules following coronary microembolization induced by homologous microthrombi in rats,” Chinese Journal of Integrative Medicine, vol. 17, no. 12, pp. 917–924, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Chen, X. Wu, H. Wu, and H. Wang, “A randomized controlled trial of adjunctive Bunchang Naoxintong capsule versus maintenance dose clopidogrel in patients with CYP2C19*2 polymorphism,” Chinese Journal of Integrative Medicine, vol. 20, no. 12, pp. 894–902, 2014. View at Publisher · View at Google Scholar
  21. H. Chen, G. Yu, H. Sun, X. Wu, and H. Wang, “Comparison of adjunctive naoxintong versus clopidogrel in volunteers with the CYP2C19 * 2 gene mutation accompanied with qi deficiency and blood stasis constitution,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 207034, 10 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Su, J. Duan, W. Cui et al., “Network-based biomarkers for cold coagulation blood stasis syndrome and the therapeutic effects of Shaofu Zhuyu decoction in rats,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 901943, 15 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. H.-X. Li, S.-Y. Han, X.-W. Wang et al., “Effect of the carthamins yellow from Carthamus tinctorius L. on hemorheological disorders of blood stasis in rats,” Food and Chemical Toxicology, vol. 47, no. 8, pp. 1797–1802, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Su, J. Duan, W. Cui et al., “Network-based biomarkers for cold coagulation blood stasis syndrome and the therapeutic effects of shaofuzhuyu decoction in rats,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 901943, 15 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Liu, J.-A. Duan, Y. Tang et al., “Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation,” Journal of Ethnopharmacology, vol. 139, no. 2, pp. 381–387, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. U. H. Frey, N. Aral, N. Müller, and W. Siffert, “Cooperative effect of GNB3 825C>T and GPIIIa PI(A) polymorphisms in enhanced platelet aggregation,” Thrombosis Research, vol. 109, no. 5-6, pp. 279–286, 2003. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Wang, X. Xiong, and B. Feng, “Aspirin resistance and promoting blood circulation and removing blood stasis: current situation and prospectives,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 954863, 11 pages, 2014. View at Publisher · View at Google Scholar
  28. Q.-H. Shang, H. Xu, X.-Y. Lu, C. Wen, D.-Z. Shi, and K.-J. Chen, “A multi-center randomized double-blind placebo-controlled trial of Xiongshao Capsule in preventing restenosis after percutaneous coronary intervention: a subgroup analysis of senile patients,” Chinese Journal of Integrative Medicine, vol. 17, no. 9, pp. 669–674, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. K.-J. Chen, D.-Z. Shi, H. Xu et al., “XS0601 reduces the incidence of restenosis: a prospective study of 335 patients undergoing percutaneous coronary intervention in China,” Chinese Medical Journal, vol. 119, no. 1, pp. 6–13, 2006. View at Google Scholar · View at Scopus
  30. S.-K. Jeong, Y. I. Cho, M. Duey, and R. S. Rosenson, “Cardiovascular risks of anemia correction with erythrocyte stimulating agents: should blood viscosity be monitored for risk assessment?” Cardiovascular Drugs and Therapy, vol. 24, no. 2, pp. 151–160, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. P. J. O'Brien, H. Koi, S. Parry et al., “Thrombin receptors and protease-activated receptor-2 in human placentation: receptor activation mediates extravillous trophoblast invasion in vitro,” The American Journal of Pathology, vol. 163, no. 4, pp. 1245–1254, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. E. Novoa, W. H. Seegers, and H. I. Hassouna, “Improved procedures for the purification of selected vitamin K dependent proteins,” Preparative Biochemistry, vol. 6, no. 5, pp. 307–338, 1976. View at Publisher · View at Google Scholar · View at Scopus
  33. R. Carreras-Torres, G. Athanasiadis, M. Via et al., “Allele-allele interaction within the F13A1 gene: a risk factor for ischaemic heart disease in Spanish population,” Thrombosis Research, vol. 126, no. 3, pp. e241–e245, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. Z. Bereczky, E. Balogh, É. Katona et al., “Modulation of the risk of coronary sclerosis/myocardial infarction by the interaction between factor XIII subunit A Val34Leu polymorphism and fibrinogen concentration in the high risk Hungarian population,” Thrombosis Research, vol. 120, no. 4, pp. 567–573, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Karimi, Z. Bereczky, N. Cohan, and L. Muszbek, “Factor XIII deficiency,” Seminars in Thrombosis and Hemostasis, vol. 35, no. 4, pp. 426–438, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. S. A. Park, B. L. Park, J. H. Park et al., “Association of polymorphisms in thromboxane A2 receptor and thromboxane A synthase 1 with cerebral infarction in a Korean population,” BMB Reports, vol. 42, no. 4, pp. 200–205, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. M. Aggarwal and R. McKenna, “Update on carbonic anhydrase inhibitors: a patent review (2008–2011),” Expert Opinion on Therapeutic Patents, vol. 22, no. 8, pp. 903–915, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. L. Alaei., A. A. Moosavi-Movahedi, H. Hadi., A. A. Saboury., F. Ahmad, and M. Amani, “Thermal inactivation and conformational lock of bovine carbonic anhydrase,” Protein and Peptide Letters, vol. 19, no. 8, pp. 852–858, 2012. View at Publisher · View at Google Scholar · View at Scopus