The Preventive Effect on Ethanol-Induced Gastric Lesions of the Medicinal Plant Plumeria rubra: Involvement of the Latex Proteins in the NO/cGMP/K_ATP Signaling Pathway

Table 1

Semi-quantitative evaluation of gastric lesions.

Groups	Microscopic scores
	Hemorrhage	Loss epithelial cell	Inflammatory infiltrate
Negative control group	0 (0-0)	0 (0-0)	0 (0-0)
Positive control group	4 (4-4)	3 (2-3)	1 (0-1)
PrLP	0.5 (0-1)	1 (1-1)	0 (0-1)
NAC	0 (0-0)	1 (1-1)	0 (0-1)

Data represent the median and range of scores from two separate experiments: (0) absent, (1) mild, (2) moderate, (3) intense, (4) edema in the upper mucosa, hemorrhagic damage, epithelial cell loss and the presence of inflammatory cells. indicates a significant difference compared with the negative control group. indicates a significant difference compared with the positive control group (vehicle). ( animals/group, Kruskal-Wallis test followed by Dunn’s test).