Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 2

Mean and change in mean subjective sleep parameters.

	SZRT group ()		Placebo group ()		P value^a
	Mean (SD)	Change	Mean (SD)	Change
PSQI
Total scores
Baseline	11.6 (3.6)		11.5 (2.5)
4-week posttreatment	7.8 (3.7)	−3.8	9.6 (3.1)	−1.9	0.007
Sleep diary
Total time in bed
Baseline	446.6 (104.2)		489.8 (111.5)
4-week posttreatment	466.3 (78.8)	24.1	481.7 (113.6)	−5.5	0.261
Mean TST
Baseline	342.6 (95.2)		377.0 (101.1)
4-week posttreatment	412.8 (81.3)	70.2	418.8 (121.9)	41.8	0.228
Mean SL
Baseline	41.5 (36.7)		38.8 (18.9)
4-week posttreatment	26.5 (18.3)	−15.0	31.8 (31.5)	−6.9	0.211
Mean SE (%)
Baseline	76.5 (11.3)		79.0 (11.1)
4-week posttreatment	87.9 (9.0)	11.4	84.1 (15.4)	5.0	0.017

Difference between mean change scores SZRT and placebo groups (-test). TST, total sleep time; SL, sleep latency; SE, sleep efficiency.
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