Anticancer Activity of Saponins from Allium chinense against the B16 Melanoma and 4T1 Breast Carcinoma Cell

Figure 1

Effects of ACS treatment on the morphologies of B16 and 4T1 cells. B16 and 4T1 cells were treated with different concentrations of ACSs (100, 200, and 300 μg/mL). The cells were divided into three groups: the positive group (5-Fu; 30 μg/mL), the negative group (PBS; 100 μL), and the control group. (a) Representative images showing the morphological changes in B16 and 4T1 cells after being treated with different concentrations of ACSs (original magnification ×10). (b) Representative images showing the morphological changes in B16 and 4T1 cells dyed with Giemsa after being treated with different concentrations of ACSs (original magnification, ×100). (c) Representative images showing the morphological changes in B16 and 4T1 cells dyed with HE after being treated with different concentrations of ACSs (original magnification, ×10).

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