Antihypertensive Effect of Radix Paeoniae Alba in Spontaneously Hypertensive Rats and Excessive Alcohol Intake and High Fat Diet Induced Hypertensive Rats
Table 1
Effect of Radix Paeoniae Alba extract on the body weight of rats.
Group
Parameter
Initial weight (g)
Final weight (g)
Weight gain (g)
SD normal ( = 7)
245.50 ± 15.69
423.00 ± 26.05
178.38 ± 26.05
ACHFD rats ()
control
246.10 ± 19.47
427.00 ± 12.18
181.75 ± 19.59
cap
237.40 ± 8.06
426.00 ± 23.71
189.43 ± 21.02
PH
243.90 ± 13.98
420.67 ± 38.50
175.78 ± 38.32
PL
244.30 ± 9.57
417.00 ± 28.52
170.78 ± 33.40
WKY normal ( = 8)
328.00 ± 24.54
343.13 ± 23.50
15.13 ± 28.80
SHR control ( = 8)
335.88 ± 23.13
333.25 ± 16.20
−2.63 ± 20.58
SHR cap ( = 8)
329.25 ± 24.50
349.25 ± 32.88
20.00 ± 14.73
SHR PH ( = 8)
332.38 ± 24.85
342.50 ± 27.32
10.13 ± 30.65
SHR PL ( = 8)
342.63 ± 27.24
353.50 ± 29.17
10.88 ± 20.41
ACHFD: Alcohol in conjunction with a high fat diet; cap: captopril; PH: RPA extract high dose group (75 mg/kg); PL: RPA extract low dose group (25 mg/kg).