Research Article

Antihypertensive Effect of Radix Paeoniae Alba in Spontaneously Hypertensive Rats and Excessive Alcohol Intake and High Fat Diet Induced Hypertensive Rats

Table 1

Effect of Radix Paeoniae Alba extract on the body weight of rats.

GroupParameterInitial weight (g)Final weight (g)Weight gain (g)

SD normal ( = 7)245.50 ± 15.69423.00 ± 26.05178.38 ± 26.05
ACHFD rats ()control246.10 ± 19.47427.00 ± 12.18181.75 ± 19.59
cap237.40 ± 8.06426.00 ± 23.71189.43 ± 21.02
PH243.90 ± 13.98420.67 ± 38.50175.78 ± 38.32
PL244.30 ± 9.57417.00 ± 28.52170.78 ± 33.40

WKY normal ( = 8)328.00 ± 24.54343.13 ± 23.5015.13 ± 28.80
SHR control ( = 8)335.88 ± 23.13333.25 ± 16.20−2.63 ± 20.58
SHR cap ( = 8)329.25 ± 24.50349.25 ± 32.8820.00 ± 14.73
SHR PH ( = 8)332.38 ± 24.85342.50 ± 27.3210.13 ± 30.65
SHR PL ( = 8)342.63 ± 27.24353.50 ± 29.1710.88 ± 20.41

ACHFD: Alcohol in conjunction with a high fat diet; cap: captopril; PH: RPA extract high dose group (75 mg/kg); PL: RPA extract low dose group (25 mg/kg).