Effects of Traditional Chinese Medicine on Chemotherapy-Induced Myelosuppression and Febrile Neutropenia in Breast Cancer Patients

Figure 4

The rates of severe chemotherapy-induced neutropenia (Grades III-IV) for the entire propensity-matched patients in different chemotherapy regimens. After matching, patients in group 2 had a higher rate of severe neutropenia compared to patients in group 1 who received chemotherapy regimens 1, 2, and 3 treatment (20% versus 19%, ; 6% versus 3%, ; 41% versus 35%, , resp.). However, patients in group 1 had a higher rate of severe neutropenia compared to patients in group 2 who received chemotherapy regimen 4 treatment (15% versus 12%, ). Chemotherapy. 1: the chemotherapy regimens contain AC/EC (Adriamycin or epirubicin, Cyclophosphamide), CAF/CEF (Adriamycin or epirubicin, Cyclophosphamide, and 5-Fluorouracil). 2: the chemotherapy regimens contain TC (paclitaxel or docetaxel, Cyclophosphamide) and T (paclitaxel or docetaxel). 3: the chemotherapy regimens contain anthracyclines combined with paclitaxel or docetaxel: TAC/TEC (paclitaxel or docetaxel, Cyclophosphamide, and Adriamycin or epirubicin); TA/TE (paclitaxel or docetaxel, Adriamycin or epirubicin). 4: the chemotherapy regimens contain anthracyclines followed by paclitaxel or docetaxel: AC/EC (Adriamycin or epirubicin, Cyclophosphamide); CAF/CEF (Adriamycin or epirubicin, Cyclophosphamide, and 5-Fluorouracil), followed with T or TH (paclitaxel or docetaxel, Herceptin).