Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 736197, 11 pages
http://dx.doi.org/10.1155/2015/736197
Research Article

Effects of Traditional Chinese Medicine on Chemotherapy-Induced Myelosuppression and Febrile Neutropenia in Breast Cancer Patients

1Department of Breast Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Road, Guangzhou 510120, China
2Department of Breast Surgery, Guangdong Hospital of Traditional Chinese Medicine, Traditional Chinese Medicine University of Guangzhou, 111 Dade Road, Guangzhou 510120, China
3Department of Hepatic Surgery, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou 510630, China
4Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshaner Road, Guangzhou 510080, China

Received 14 March 2015; Revised 26 May 2015; Accepted 3 June 2015

Academic Editor: Richard Pietras

Copyright © 2015 Huan Tian et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Crawford, D. C. Dale, and G. H. Lyman, “Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management,” Cancer, vol. 100, no. 2, pp. 228–237, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. A. G. Freifeld, E. J. Bow, K. A. Sepkowitz et al., “Executive summary: clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America,” Clinical Infectious Diseases, vol. 52, no. 4, pp. 427–431, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Bosly, D. Bron, A. Van Hoof et al., “Achievement of optimal average relative dose intensity and correlation with survival in diffuse large B-cell lymphoma patients treated with CHOP,” Annals of Hematology, vol. 87, no. 4, pp. 277–283, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. I. Chirivella, B. Bermejo, A. Insa et al., “Optimal delivery of anthracycline-based chemotherapy in the adjuvant setting improves outcome of breast cancer patients,” Breast Cancer Research and Treatment, vol. 114, no. 3, pp. 479–484, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Pettengell, H. E. Johnson, P. J. Lugtenburg et al., “Impact of febrile neutropenia on R-CHOP chemotherapy delivery and hospitalizations among patients with diffuse large B-cell lymphoma,” Supportive Care in Cancer, vol. 20, no. 3, pp. 647–652, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. L. Yi-Hsien and C. Jen-Hwey, “Use of Chinese medicine by women with breast cancer: a nationwide cross-sectional study in Taiwan,” Complementary Therapies in Medicine, vol. 19, no. 3, pp. 137–143, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. C.-G. Mao, Z.-Z. Tao, L.-J. Wan, J.-B. Han, Z. Chen, and B.-K. Xiao, “The efficacy of traditional Chinese Medicine as an adjunctive therapy in nasopharyngeal carcinoma: a systematic review and meta-analysis,” Journal of the Balkan Union of Oncology, vol. 19, no. 2, pp. 540–548, 2014. View at Google Scholar · View at Scopus
  8. G. Gu, I. Barone, L. Gelsomino et al., “Oldenlandia diffusa extracts exert anti-proliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation,” Journal of Cellular Physiology, vol. 227, no. 10, pp. 3363–3372, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. A. T. Perez, B. Arun, D. Tripathy et al., “A phase 1B dose escalation trial of Scutellaria barbata (BZL101) for patients with metastatic breast cancer,” Breast Cancer Research and Treatment, vol. 120, no. 1, pp. 111–118, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. A. G. Freifeld, E. J. Bow, K. A. Sepkowitz et al., “Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America,” Clinical Infectious Diseases, vol. 52, no. 4, pp. e56–e93, 2011. View at Publisher · View at Google Scholar
  11. M. S. Aapro, J. Bohlius, D. A. Cameron et al., “2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours,” European Journal of Cancer, vol. 47, no. 1, pp. 8–32, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Ross and G. R. Robert, “R: a language for data analysis and graphics,” Journal of Computational and Graphical Statistics, vol. 5, no. 3, pp. 299–314, 1996. View at Google Scholar · View at Scopus
  13. L. Xu, H. Li, Z. Xu et al., “Multi-center randomized double-blind controlled clinical study of chemotherapy combined with or without traditional Chinese medicine on quality of life of postoperative non-small cell lung cancer patients,” BMC Complementary and Alternative Medicine, vol. 12, article 112, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Zhong, H.-D. Li, D.-Y. Liu et al., “Clinical study of hepatectomy combined with Jianpi Huayu therapy for hepatocellular carcinoma,” Asian Pacific Journal of Cancer Prevention, vol. 15, no. 14, pp. 5951–5957, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. Y.-H. Huang, J.-L. Chen, S.-H. Yang, G.-H. Liu, K.-P. Chang, and N.-M. Tsang, “Influence of Chinese medicine on weight loss and quality of life during radiotherapy in head and neck cancer,” Integrative Cancer Therapies, vol. 12, no. 1, pp. 41–49, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Xu, A. G. Zhao, Z. Y. Li et al., “Survival benefit of traditional chinese herbal medicine (a herbal formula for invigorating spleen) for patients with advanced gastric cancer,” Integrative Cancer Therapies, vol. 12, no. 5, pp. 414–422, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Liu, H. Tan, X. Zhang et al., “Hematopoietic effects and mechanisms of Fufang Ejiao Jiang on radiotherapy and chemotherapy-induced myelosuppressed mice,” Journal of Ethnopharmacology, vol. 152, no. 3, pp. 575–584, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. A.-B. Zhao, B. Yu, X.-L. Wu et al., “Protective effects on myelosuppression mice treated by three different classic Chinese medicine formulae,” Pharmacognosy Magazine, vol. 7, no. 26, pp. 133–140, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Liu, J. Li, F. Y. Meng et al., “Polysaccharides from the root of Angelica sinensis promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway,” BMC Complementary and Alternative Medicine, vol. 10, article 79, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. L.-F. Wang, Z.-Y. Xu, C.-J. Jin et al., “Dual regulation of cell cycles by Shuanghuang Shengbai Granule in Lewis-bearing mice with chemotherapy-induced myelosuppression and its mechanism,” Zhong Xi Yi Jie He Xue Bao, vol. 7, no. 5, pp. 453–457, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. A. P. Mullard, V. Misra, P. Sumra, Z. Ali, S. M. O'Reilly, and Z. Malik, “Reducing febrile neutropenia rates in early breast cancer. Experience of two UK cancer centres,” Supportive Care in Cancer, vol. 22, no. 8, pp. 2033–2037, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. K. Chen, X. L. Zhang, H. R. Deng et al., “Clinical predictive models for chemotherapy-induced febrile neutropenia in breast cancer patients: a validation study,” PLoS ONE, vol. 9, no. 6, Article ID e96413, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Schwenkglenks, R. Pettengell, C. Jackisch et al., “Risk factors for chemotherapy-induced neutropenia occurrence in breast cancer patients: data from the INC-EU Prospective Observational European Neutropenia Study,” Supportive Care in Cancer, vol. 19, no. 4, pp. 483–490, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Jolis, F. Carabantes, S. Pernas et al., “ncidence of chemotherapy-induced neutropenia and current practice of prophylaxis with granulocyte colony-stimulating factors in cancer patients in Spain: a prospective, observational study,” European Journal of Cancer Care, vol. 22, no. 4, pp. 513–521, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. J. A. Chiarotto and G. Dranitsaris, “Full-dose chemotherapy in early stage breast cancer regardless of absolute neutrophil count and without G-CSF does not increase chemotherapy-induced febrile neutropenia,” Supportive Care in Cancer, vol. 21, no. 10, pp. 2727–2731, 2013. View at Publisher · View at Google Scholar · View at Scopus