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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 736197, 11 pages
Research Article

Effects of Traditional Chinese Medicine on Chemotherapy-Induced Myelosuppression and Febrile Neutropenia in Breast Cancer Patients

1Department of Breast Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Road, Guangzhou 510120, China
2Department of Breast Surgery, Guangdong Hospital of Traditional Chinese Medicine, Traditional Chinese Medicine University of Guangzhou, 111 Dade Road, Guangzhou 510120, China
3Department of Hepatic Surgery, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou 510630, China
4Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, 74 Zhongshaner Road, Guangzhou 510080, China

Received 14 March 2015; Revised 26 May 2015; Accepted 3 June 2015

Academic Editor: Richard Pietras

Copyright © 2015 Huan Tian et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

This supplementary material was to show the efficacy of chemotherapy regimens and tumor staging for chemotherapy-induced leukopenia, neutropenia and FN more deeply.

In Supporting Table 1–3, Patients in TCM treatment showed a benefit in relieving chemotherapy-induced leukopenia and FN in most chemotherapy regimens in various degrees, but little benefit in chemotherapy-induced neutropenia.

In Supporting Table 4–6, among patients at stage I or II, severe leukopenia, and FN were significantly lower in TCM treatment group. Among patients at stage III, TCM treatment showed little effect.

As to the toxicity of TCM, there was no patient suffering from renal damage during the chemotherapy in TCM treatment group. Hepatic dysfunction could be found in both groups, and there was no significant difference.

  1. Supplementary Material