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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 737631, 6 pages
Research Article

Serum Levels of Stress Hormones and Oxidative Stress Biomarkers Differ according to Sasang Constitutional Type

1Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University, 176-9 Daeheung-ro, Jung-gu, Daejeon 302-724, Republic of Korea
2Department of Health Service Management, Daejeon University, 62 Daehak-ro Yongun-dong, Song-gu, Daejeon 300-716, Republic of Korea

Received 18 January 2015; Revised 24 March 2015; Accepted 26 March 2015

Academic Editor: Salih Mollahaliloglu

Copyright © 2015 Hyeong Geug Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. This study investigated whether Sasang constitutional type is associated with differences in the serum levels of stress hormones and oxidative stress. Methods. A total of 236 participants (77 males and 159 females) were enrolled. The serum levels of cortisol, adrenaline, reactive oxygen species (ROS), and malondialdehyde (MDA) were analyzed. Results. The distribution of Sasang constitutional types was as follows: Taeumin, 35.6%; Soumin, 33.0%; and Soyangin, 31.4%. The serum cortisol levels of Taeumin were significantly lower than Soumin ( in both sexes) and Soyangin ( in males and in females). The adrenaline levels were also significantly lower in Taeumin than in Soumin ( in males and in females) and Soyangin ( in males). Serum ROS levels were significantly higher in Soyangin than in Taeumin and Soumin ( in males), whereas MDA levels were significantly lower in Taeumin compared with Soumin and Soyangin ( in males and in females). Conclusion. Taeumin type may tolerate psychological or oxidative stress better than other types, which suggests a biological mechanism to explain the different pathophysiological features of Sasang constitutional types.